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Common ligands include antibodies, peptides, and small molecules, with key targeting receptors such as transferrin receptor (TfR), lactoferrin receptor (LfR) and LRP-1 (Huang et al., 2024a

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The hepatocyte growth factor (HGF)/c-MET pathway is upregulated in PC and mediates the interaction between cancer cells and stromal pancreatic stellate cells (PSCs)

BPC-157 shows significant in vitro stability in gastric juice (over 24 hours) and moderate plasma stability (up to four hours), with detectability in urine for at least four days ex vivo [2, 4]